Ronald L Schnaar Selected Research

Sialic Acid Binding Immunoglobulin-like Lectins

1/2022	Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease.
2/2020	Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-κB pathway.
1/2017	Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties.
2/2016	Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression.
11/2015	Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner.
3/2015	Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells.
1/2014	Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation.

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Ronald L Schnaar Research Topics

Disease

16	Inflammation (Inflammations) 01/2021 - 08/2002
8	Neoplasms (Cancer) 01/2019 - 02/2006
5	Neoplasm Metastasis (Metastasis) 03/2011 - 02/2006
4	Guillain-Barre Syndrome 02/2011 - 08/2004
4	Carcinoma (Carcinomatosis) 03/2009 - 02/2006
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2016
3	Rhinosinusitis 01/2021 - 03/2015
3	Infections 01/2021 - 11/2015
3	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2018 - 09/2014
3	Intellectual Disability (Idiocy) 01/2018 - 09/2014
3	Seizures (Absence Seizure) 01/2018 - 05/2010
3	Nervous System Trauma 01/2016 - 07/2006
3	Spinal Cord Injuries (Spinal Cord Injury) 02/2013 - 06/2010
2	Nervous System Diseases (Neurological Disorders) 12/2021 - 07/2010
2	Hereditary Spastic Paraplegia 01/2018 - 01/2016
2	Epilepsy (Aura) 01/2016 - 07/2015
1	Stroke (Strokes) 01/2022
1	Polyps 01/2021
1	Brain Neoplasms (Brain Tumor) 01/2021
1	Neuralgia (Stump Neuralgia) 01/2020
1	Hypersensitivity (Allergy) 01/2020
1	Communicable Diseases (Infectious Diseases) 01/2019
1	Atherosclerosis 01/2019
1	Diabetic Angiopathies (Diabetic Angiopathy) 01/2019
1	Histoplasmosis 01/2019
1	Gliosis 01/2017
1	Pneumonia (Pneumonitis) 01/2017
1	Obesity 01/2017
1	Insulin Resistance 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2016
1	Parkinson Disease (Parkinson's Disease) 01/2016
1	Paraplegia (Spastic Paraplegia) 07/2015
1	Memory Disorders (Memory Loss) 09/2014
1	Autistic Disorder (Autism) 04/2014
1	Bipolar Disorder (Manic Depressive Psychosis) 04/2014
1	Mental Disorders (Mental Disorder) 04/2014
1	Schizophrenia (Dementia Praecox) 04/2014
1	Eosinophilia 01/2014
1	Contusions 11/2012
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2012
1	Ascites 08/2012
1	Ovarian Neoplasms (Ovarian Cancer) 08/2012
1	Breast Neoplasms (Breast Cancer) 03/2011

Drug/Important Bio-Agent (IBA)

16	LigandsIBA 01/2022 - 02/2006
16	GangliosidesIBA 12/2021 - 03/2002
9	Polysaccharides (Glycans)IBA 01/2021 - 06/2002
7	Sialic Acid Binding Immunoglobulin-like LectinsIBA 01/2022 - 01/2014
5	Protein Isoforms (Isoforms)IBA 01/2021 - 02/2006
5	L-SelectinIBA 03/2009 - 06/2002
5	SelectinsIBA 03/2009 - 02/2006
4	E-SelectinIBA 03/2011 - 06/2004
4	AntibodiesIBA 03/2011 - 07/2008
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2009
3	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2021 - 03/2015
3	SialyltransferasesIBA 01/2017 - 01/2014
3	Carrier Proteins (Binding Protein)IBA 01/2016 - 10/2009
3	CytokinesIBA 01/2014 - 03/2011
3	Neuraminidase (Sialidase)IBA 02/2013 - 02/2007
3	P-SelectinIBA 03/2009 - 02/2007
2	Monoclonal AntibodiesIBA 01/2022 - 03/2011
2	LectinsIBA 01/2021 - 10/2008
2	EpitopesIBA 01/2021 - 03/2011
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019 - 02/2006
2	LipidsIBA 01/2019 - 08/2012
2	EnzymesIBA 01/2016 - 02/2013
2	GlycosphingolipidsIBA 03/2011 - 06/2004
2	CarbohydratesIBA 03/2011 - 11/2008
2	Myelin-Associated GlycoproteinIBA 10/2009 - 06/2004
2	Heparin (Liquaemin)FDA LinkGeneric 02/2007 - 06/2002
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Sialic Acid Binding Ig-like Lectin 3IBA 01/2021
1	Death Domain ReceptorsIBA 01/2021
1	Toll-Like Receptor 2IBA 01/2020
1	trisialoganglioside GT1IBA 01/2020
1	Proteoglycans (Proteoglycan)IBA 10/2018
1	(N- acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferaseIBA 01/2018
1	haematoside synthetaseIBA 01/2018
1	Nogo ReceptorsIBA 01/2017
1	SynucleinsIBA 01/2016
1	Sialic Acid Binding Ig-like Lectin 1IBA 11/2015
1	Sialic AcidsIBA 11/2015
1	SialoglycoproteinsIBA 07/2015
1	Glutamate Receptors (Glutamate Receptor)IBA 09/2014
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 09/2014
1	Adenosine Triphosphatases (ATPase)IBA 09/2014
1	polysialic acidIBA 04/2014
1	ChemokinesIBA 01/2014
1	OvalbuminIBA 01/2014
1	Chondroitin ABC LyaseIBA 02/2013
1	AntioxidantsIBA 11/2012
1	Glutathione (Reduced Glutathione)IBA 11/2012
1	Messenger RNA (mRNA)IBA 11/2012
1	CalciumIBA 11/2012
1	sulforaphaneIBA 11/2012
1	Neuroprotective AgentsIBA 11/2012
1	Glutamic Acid (Glutamate)FDA Link 11/2012
1	GD3 ganglioside (GD(3))IBA 08/2012

Therapy/Procedure

4	Therapeutics 02/2013 - 07/2006
2	Microspheres (Microsphere) 06/2008 - 02/2006
1	Enzyme Therapy 02/2013